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Therefore, despite being only a partial effector of carcinogenesis, CBS belongs to a panel of intervening players, including NF-κB, KRAS, p53 and Wnt components, that contribute to metabolic rewiring and increased proliferative and invasive potential
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Based on the mechanism of skin irritation, we examined and proposed an approach to assess the skin irritation potential of copper compounds using cytotoxicity assay, gene and protein expression levels of cytokines
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